Gardens morphing into spirals: Researchers examine what it’s like to trip on Salvia divinorum

first_imgShare on Facebook Pinterest A team of researchers recently investigated the subjective psychological effects of the psychedelic plant known as Salvia divinorum.“Our main findings indicate that smoked [Salvia divinorum] facilitates an intense altered state of consciousness consisting of marked changes in affect, cognition, interoception, and sense of reality,” Peter H. Addy of VA Connecticut Healthcare System and his colleagues wrote in their study, which was published in the April 2015 issue of the Journal of Psychopharmacology. “Individuals often lost normal awareness of themselves and their surroundings, as well as reporting an assortment of delusional phenomena.”Salvia divinorum is a unique drug with a intense onset and short duration that has been used in Mexican healing rituals for hundreds of years. Share Share on Twittercenter_img Email LinkedIn Classic psychedelics like LSD or psilocybe mushrooms act as agonists of serotonin receptors, meaning the drugs activate receptors in the brain in a manner similar to natural serotonin. But salvinorin A, the main psychoactive component in Salvia divinorum, has a completely different mechanism of action. Rather than targeting the serotonin system, salvinorin A acts as an agonist of kappa opioid receptors.In the study, 32 medically and psychiatrically healthy adults who had prior experience with psychedelic drugs smoked 1017 micrograms of salvinorin A in a controlled, relaxed setting.The participants uniformly reported a rapid onset and extremely intense experience. “The transition between states was abrupt, very abrupt and that was a little unpleasant,” one participant told the researchers.The participants experienced a wide variety of hallucinations after smoking Salvia divinorum. Seventeen participants reported synesthesia, the experience of two or more sensory channels being mixed together. Twenty-five participants said they experienced closed eye visual imagery, from simple lights to geometric patterns to complex scenic hallucinations.“What had been a bit of light entering through the bottoms of the eye mask became two voluminous hills or waves, and then they were supplemented by others that extended outwards into a horizon,” one of the participants said.Surprisingly, five participants experienced the same scenic hallucination: carnival scenes. But other participants reported their visual hallucinations as kaleidoscopic, with one person them describing them as “garden images morphing into spirals.”The Salvia divinorum plant (Photo credit: Luis Pérez)Tactile and kinesthetic sensations were also common. Many participants reported feeling as if their body was moving, spinning, or stretching. Four participants reported a specifically odd sensation: being folded along with the universe around them. “The field was solid, but I was falling through the field and then there was a diamond shaped pattern,” one person explained. “I was falling through the pattern, and it was all folding in, and it was falling away from me.”Six participants reported not hearing anything during the psychedelic experience, while five other participants reported hearing auditory hallucinations or less well-defined auditory sensations.The participants also reported a wide variety of emotional shifts. Some participants felt happy or humorous, while others felt guilty, selfish, or frightened. The most commonly reported emotional states were self-acceptance and awe.A disruption of the normal sense of self emerged as another feature of the experience. Eleven participants reported feeling a sense of detachment from themselves, while six reported feeling disconnected from their bodies. “I couldn’t tell if I was part of the carpet, or you’re part of the chair,” one person explained.Fifteen participants said the experience was unique, while six described it as a crazy. According to one participant: “That’s crazy. I’ve never felt anything like that… It was like a crazy dramatic river scene.”The researchers said the Salvia divinorum appears to have a low potential for abuse. “Subjects did not report experiencing euphoria or craving to use, and did not seek out SD subsequent to experimental exposure,” the researchers said.last_img read more

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What happens next? Colin Sinclair’s reforecast for 2020 and beyond

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AG&P’s scalable LNG supply chain model

first_imgGet instant access to must-read content today!To access hundreds of features, subscribe today! At a time when the world is forced to go digital more than ever before just to stay connected, discover the in-depth content our subscribers receive every month by subscribing to gasworld.Don’t just stay connected, stay at the forefront – join gasworld and become a subscriber to access all of our must-read content online from just $270. Subscribelast_img

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Some feat

first_imgThere can be no excuse for hopping in a cab for Herbert Smith staff in the next month. More than 220 employees have signed up to a charity walk that will count every step they take over the next four weeks. Every volunteer will be fitted with a pedometer, with participants aiming to collectively walk as far as Zambia (just short of 5,000 miles from London to its capital, Lusaka), in aid of the firm’s charity of the year, WaterAid. As well as hundreds of staff from the London office taking part, there will also be contributions from offices in Moscow, Madrid, Abu Dhabi, Dubai, Singapore, Paris and Brussels. Looks like the firm is stepping up its charity efforts.last_img read more

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Busy month for Aaras

first_imgOn September 4, Helian Brother arrived at Karachi Port where Aaras was on hand to discharge 997 pieces for the Jinnah Barrage power plant, power generators for a cement factory, dump trucks, hot rolled steel, coils, turbines and other project cargo; the consignment had a total weight of around 5,523 tonnes. Han Yi called at Port Qasim on September 14, 2014 and Aaras handled approximately 60 project cargo loads for Attack Refinery Limited, with a total weight of 271.5 tonnes. Han Yi continued to Karachi Port on Sept 15, 2014  to discharge four sets of transformers from Iran Power and Water Equipment and Services, which the Aaras team successfully delivered to local consignee NTDC, Wapda, Lahore. These heavy pieces had a total weight of approximately 623 tonnes. In both cases, Aaras Project and Logistics – a member to the Worldwide Project Consortium (WWPC) for Pakistan through its affiliate Aaras Shipping Agencies – delivered the cargoes directly to the consignee on a under hook / hook basis. The company also arranged inland transportation from the respective vessel’s berth to designated stowage areas allotted by Karachi Port and the Port Qasim Authority.Han Yi discharges Attack Refinery load www.aaras-projects.com www.aarasshipping.com www.wwpc.eu.comlast_img read more

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Court sparring begins in legal aid contract challenges

first_imgLitigation over the government’s award of new criminal legal aid contracts will not be ‘straightforward’, the High Court heard yesterday during a lengthy hearing on how 115 procurement law challenges and a judicial review should be managed.Hearing the lord chancellor’s application for a possible group litigation order in the Royal Courts of Justice for nearly three hours, Mr Justice Stuart-Smith (pictured) said the litigation would require ‘exorbitant effort by everyone’, including himself and court staff.‘We have got to find a balance between imposing unnecessary work on people while at the same time ensuring all litigation is resolved in a quick way,’ he said.Sarah Hannaford QC, representing the lord chancellor, told the court that 115 part 7 claims and one judicial review had been issued. The exact number of letters before action had not been recorded, but around 142 responses to letters before action were sent. Hannaford said her client was ’very keen’ to move into the new criminal contracting regime and had been ’extremely reluctant’ to delay its commencement from 11 January to 1 April. Dealing with the challenges, Hannaford said, was a ‘monumental task’. But the defence had ’no particular axe to grind’ on which route for case management should be taken – a group litigation order or ’simple, more generalised’ case management option.Stuart-Smith did not grant the group order sought by the lord chancellor. Instead, claimants must identify five ’lead’ cases by Friday. Should they be unable to reach agreement, the cases will be chosen randomly by the judge. The lord chancellor can pick three ’lead’ cases. The lord chancellor must plead defences to the eight cases in the next 21 days. Stuart-Smith stayed the other claims.The choice of lead cases ’may be dictated’ by the ability to finance them or how they are to be financed, Stuart-Smith said.’At the moment, I do not see this as either necessarily or most likely resulting in a trial as such,’ he added. ’I’m not wedded to the idea of using a test case.’A Guidance for Assessors document used in the awards stage of the tender process must be disclosed to all parties in the next seven days, Stuart-Smith ruled. Additional disclosure of underlying documents in relation to the marking and moderation of tender applications was ordered for the claimants’ lead cases.Particulars of claim for all cases must be filed within 14 days subject to any other extension granted. The next hearing is scheduled for 16 December.Stuart-Smith said he had ‘not even begun’ reading papers in relation to judicial review proceedings issued by the recently established Fair Crime Contracts Alliance and London Borough of Newham.Hannaford told the court the lord chancellor ’will be putting in an objection’ for an application of urgent consideration of the JR prior to the part 7 claims.The second hearing ’will address the state of the JR as well’, Stuart-Smith said.last_img read more

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Claims manager fined £70,000 as new regulator flexes muscles

first_imgA claims management company has been fined £70,000 for misleading consumers through its websites and printed materials in the first such action by the sector’s new regulator. The fine follows the transfer of regulatory responsibility for claims management companies (CMCs) from the Ministry of Justice to the Financial Conduct Authority on 1 April. The switch in regulator was widely seen as ushering in a tougher regime. According to the FCA, Professional Personal Claims (PPC) Limited websites and printed materials prominently displayed the logos of five major banks, suggesting to consumers that their claims for mis-sold payment protection insurance (PPI) were going directly to the banks. In reality they were engaging PPC as a claims manager to pursue claims in return for payment of a success fee.PPC also failed to present accurate, fully formed, detailed and specific complaints to banks, the FCA said. Mark Steward, executive director of enforcement and market oversight at the regulator said: ‘PPC’s misleading website and marketing material suggested PPC was associated with the five banks when this was not the case. Claims management firms must ensure their advertising is accurate. Not only in terms of what they say about themselves and their services but also in terms of what is represented.’Today’s announcement by the FCA concedes that the fine originated in an investigation by its predecessor, the Claims Management Regulator, which first imposed the penalty in December last year. The FCA took over the case during the appeal process and imposed the £70,000 fine following the withdrawal of the appeal in September.last_img read more

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Mexican sales spur progress

first_imgTENDERING for the 50-year concession to operate Mexico’s 1480 km Sureste Railway began on February 18. Connecting Mexico City with the Gulf coast ports of Veracruz and Coatzacoalcos, the line carries almost 9% of the country’s rail freight. The government has set June 11 as the deadline for submitting bids, and hopes to select a concessionaire by July 3. No minimum price has been set on this occasion. Amongst the firms expecting to bid is Illinois Central, now owned 75% by Canadian National (RG 3.98 p140). The winner will also be given an option to buy the Mayab railway, part of FNM’s present Sureste business, which runs from Coatzacoalcos to Merida in Yucatan.Next to be offered for sale will be the Vale do Mexico terminal railway, which connects the Sureste, Noreste and Pacifico-Norte and two regional routes in the states of Oaxaca and Chiapas. However, the government has decided not to privatise the 240 km Tehuantepec Isthmus railway, which links the ports of Coatzacoalcos and Salina Cruz, because of its strategic position as a short route between the Gulf of Mexico and the Pacific Ocean.Control of FNM’s 10460 km Pacifico-Norte network passed to the Grupo Ferroviario Mexicano consortium on February 19. Operations were suspended for a day while a new union agreement was negotiated; GFM, in which Union Pacific has a 13% stake, has taken on just 4200 of the original 14000 staff.Noreste concessionaire Transportación Ferroviaria Mexicana awarded a 17-year contract on March 2 for Motive Power Industries subsidiary MPI de Mexico to overhaul and maintain 168 diesel locos at San Luis Potosi. Worth US$419m, the deal replaces a previous contract with the government that had six years to run. MPI de Mexico maintains 151 other units under contract for TFM and other Mexican firms. TFM has ordered 75 new SD70MACs from General Motors EMD, which will be assembled at Bombardier’s former Concarril works at Sahagun. The plant started work on the first of 275 SD70MACs covered by the partnership agreement in January: a build of 130 for Burlington Northern Santa Fe using components supplied from London, Ontario. olast_img read more

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Bouyon artiste releases single celebrating Dominica

first_img 42 Views   one comment Share Sharing is caring! Share EntertainmentLocalNews Bouyon artiste releases single celebrating Dominica by: – October 19, 2013center_img One of Dominica’s bouyon songwriter/producer/recording artiste Neijel “Nayee” Jno Baptiste released a single entitled “Celebrate my Island’ at the Friday Creole Sizzle outside the LIME store in Roseau.The single has been described as a “compliment to the Dominican culture, its music and our style of celebration.”Nayee, who is scheduled to perform as a solo artiste at the annual Creole in the Park (CITP), the 17th World Creole Music Festival and other activities during Dominica’s 35th Independence celebration, said the song is not just for the Independence season.“The song makes you feel proud about the rich culture that we have and encourages you to encourage others to come to Dominica for a taste of this culture,” he said.In addition to the release of his song, the public can get a memorable piece of Nayee by purchasing his latest compilation titled “Chapter One”.According to him, ‘Chapter One’ is not an album but a compilation of the songs that he has done for the year.He also mentioned that all the songs on the compilations will not be on his official upcoming album. The compilation, which is actually a DVD, also has two of his videos on it.The public can purchase copies at either Graphics located on Great Marlborough Street or Music Land which is now located on lower King George V Street.The DVD costs $25.00 however; there is an Independence special of only $20.00 until 5th November.The former member of bouyon giant, WCK Band, mentioned that it would be great if everyone put aside all differences aside and appreciate and promote Dominica’s culture during independence.“Amongst everything going on in the country right now, it would be great if we could all put aside our differences and appreciate and support our culture. Everyone should promote our country’s culture to all our distant relatives and networks in the foreign countries,” he said.He said culture should should be neutral to build and unite the country.“Most importantly, our traditions should be taught to the younger generation so it is never lost and will always belong to Dominica,” he stated. Share Tweetlast_img read more

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Keysight Technologies Enters into Manufacturing Test License Agreement with Broadcom

first_imgKeysight Technologies announced it has entered into a manufacturing test license (MTL) agreement with Broadcom Corporation. The MTL agreement allows Keysight to provide calibration and verification test solutions to Broadcom wireless connectivity customers using the E6640A EXM Wireless Test Set. The EXM is a perfect test solution for OEMs and ODMs that need high-quality, fast, low-cost validation for wireless devices. It can test cellular, wireless connectivity, multi-satellite GNSS, digital video and other technologies in a single solution with optimized multi-device testing capabilities. Customers now have the option of using a single test set to verify wireless connectivity for improved manufacturing efficiencies and product quality. Key features of the E6640A EXM Wireless Test Set include: Up to four TRX channels per EXM. Up to 6 GHz with 160-MHz bandwidth on each TRX. Two full-duplex and two half-duplex ports per TRX. Up to 32 DUTs with multi-port adapter (MPA) technology.last_img read more

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